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To assess cost-effectiveness, a willingness-to-pay (WTP) threshold of three times the gross domestic product (GDP) per capita was used, which amounted to $36,528.3 per QALY gained in this study, following the recommendations of the World Health Organization (WHO) ( 2.6 Sensitivity analysis and price threshold analysis We performed a univariate sensitivity analysis to evaluate the impact of changing key inputs in the model, including the discount rate, initial utility, time horizon, costs, and disutility scores (Supplementary Table S5)

Ruan, Q., Yang, K., Wang, W., Jiang, L

Small molecules: Nrf2 activators, CoQ10, and NAD+ in cellular redox