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Abstract Spontaneous intracerebral hemorrhage (ICH), especially hypertensive basal ganglia hemorrhage, is a severe, often fatal stroke subtype with high morbidity and mortality

Further, while essentially all SGLT2 inhibitors have been shown to produce very similar effects on HF, progression of CKD, reduction in HbA1c and weight loss, there are major differences between the effect of different GLP-1 receptor agonists on all of these parameters

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Enzymes of the acyl-CoA thioesterase (ACOT) family, that are responsible for the deactivation of fatty acyl-CoAs, release the CoA and the esterified fatty acid