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110 Mechanistic studies have shown that combination therapy induces increased ROS and lipid peroxides and depletion of GSH, and downregulates ferroptosis inhibitory proteins, including FTH1, SLC7A11, GPX4, and FPN, 110 suggesting that -elemene is a novel inducer of ferroptosis

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"Many women use Wegovy successfully before pregnancy to improve metabolic health, lower insulin resistance, and regulate cycles - but the medication itself should not be used during conception or pregnancy." Alessandro advises anyone planning pregnancy to work with their clinician on a step-down plan and to shift focus toward nutrient density