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It inhibits the transcription of SLC7A11, leading to a reduction in cystine uptake and GSH production, thereby amplifying the cell's vulnerability to ferroptosis [61]

[DOI] [PMC free article] [PubMed] [Google Scholar] 14.**.Bahney CS

Metabolism It is involved in carbohydrate metabolism and insulin regulation, aiding in blood glucose control and overall metabolic health

However, one study reported that fentanyl causes an increase in production of reactive oxygen species in freshly isolated peripheral blood lymphocytes 118 , which arguably may involve a reduction in cellular reduced thiol levels