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Otherwise, the healing of the different tissues, which are normally not connected, would hardly provide a simultaneous wound healing effect, particularly in the most critical circumstances (Klicek et al., 2008

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Bax oligomerization is associated with the formation of openings in the OMM to allow the release of cytochrome c and other IMS proteins into the cytosol, and hence Bax oligomerization is considered a critical regulatory point in cell death (Youle and Strasser, 2008)