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pre- and post-operative treatment, when requirements are increased as in fever, severe burns, increased metabolism, pregnancy, gastrointestinal disorders interfering with intake or absorption of vitamins, prolonged or wasting diseases, alcoholism and where other deficiencies exist

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However, consistent with the between-group analyses, no statistically significant differences were detected among treatments with respect to waist circumference change

Preclinical study in mice with streptozotocin-induced diabetes that showed glucose-independent amelioration of kidney fibrosis with the DPP-4 inhibitor linagliptin