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Clinical experts are a critical part of the review team and are involved in all phases of the review process (e.g., providing guidance on the development of the review protocol, assisting in the critical appraisal of clinical evidence, interpreting the clinical relevance of the results, providing guidance on the potential place in therapy)

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For comparative research, this distinction is fundamental glucagon receptor engagement introduces lipolytic and energy expenditure pathways that dual agonist studies cannot address