Vitamin B12 (also known as cobalamin) is a single, powerful vitamin that plays a big role in energy production, red blood cell formation, and nerve function
he is a consultant with personal compensation from Aardvark Therapeutics, Altimmune, Alveus Therapeutics, Amgen, Antag, Aqua Medical, AstraZeneca, Boehringer-Ingelheim, Corcept Therapeutics, Dexcom, Eli Lilly, embecta, General Medicines Inc, GentiBio, Insulet, Kayothera, Metsera, MiniMed, Pfizer, Recordati, Roche, Sparrow Pharmaceuticals, Vertex, vTv Therapeutics, and Zealand
To improve therapeutic efficacy while minimizing side effects, combinatorial strategiesparticularly dual agonists that target both the glucagon and GLP-1 receptorsare under active investigation
Another possibility is that obesity could lower serum vitamin B12 levels through decreased dietary intake or absorption, increased catabolism, and sequestration in adipose tissue, or changes in the gut microbiota profiles which could affect the metabolism of vitamin B12
