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Some patients experience temporary discomfort that improves with treatment, while others may need ongoing management with orthotics and padding
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Nutritional adequacy requires attention, as very-low-carbohydrate diets restrict many nutrient-dense foods including fruits, whole grains, and legumes
When semaglutide is added to an existing metformin regimen, both medications can affect digestion, though they do so through different mechanismsmetformin alters gut bacteria and nutrient absorption, while semaglutide slows stomach emptying and reduces appetite signaling
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