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[DOI] [PMC free article] [PubMed] [Google Scholar] 96.Zhang Y, Zhao S, Fu Y, Yan L, Feng YL, Chen YQ, Wu YJ, Deng YL, Zhang GY, Chen ZC, Chen YH, Liu T

Ophthalmological, psychometric and therapeutic investigation in two sisters with hereditary glutathione synthetase deficiency (5-oxoprolinuria)

The fusion of cisplatin with GSH, cysteine (L(+)-Cysteine), and other proteins leads to the depletion of antioxidant reserves in the cytoplasm and causes cellular oxidative stress, which is the major mode of action of cisplatin toxicity

Individual results vary based on skin type and melanin levels