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The specific vulnerability of the gastrointestinal system to TD, in the absence of more common signs of wet and dry beriberi, may arise from direct exposure of this system to the gut microbiome and oral drugs, along with the continuous need to redistribute thiamine to other tissues

In addition, rapid weight loss regardless of the method used can temporarily alter hormone levels while the body adapts to metabolic change

In SURMOUNT-1, adults with obesity or overweight without diabetes were randomized to tirzepatide or placebo for 72 weeks

Technological advancements are blurring the boundaries between physical and digital environments and reshaping urban spaces