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Interestingly, the ghrelin receptor has been observed to increase cardiac failure and certain types of cancer, including carcinomas

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To determine if the reduction in HGP in Dpp4 / mice was mediated through the actions of hepatocyte-derived DPP4, we then measured HGP in HFHC-fed, hepatocyte-specific Dpp4 -knockout mice ( Dpp4 hep/ )