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At present, T cell-targeting immune checkpoint inhibitors have been recommended by guidelines for significant efficacy, such as programmed cell death 1/programmed death-ligand1 (PD-1/PD-L1) antibodies, cytotoxic T lymphocyteassociated protein-4 (CTLA-4) antibodies, and chimeric antigen receptor T (CAR-T)in adoptive cell therapy (ACT)

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