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The patients entered into the trial had to meet the following inclusion criteria: - erectile dysfunction secondary to radical retropubic prostatectomy, with or without bilateral sparing of the neurovascular bundles, in patients in whom the prostatectomy had been performed at least 6 months but less than 2 years prior to entry into the clinical trial

APAP-treated mice exhibited 183% of the BDNF level of control mice in the frontal cortex and 26% of the BDNF level in the parietal cortex [40,42,43]

Often referred to as the "third eye" due to its light-sensitive regulatory role, the pineal gland serves as the bodys internal timekeeper, synchronizing hormonal rhythms with environmental light cues

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