Data availability Qualified researchers may request access to individual patient-level data through the clinical study data request platform ( Further details on Roches criteria for eligible studies are available at For further details on Roches Global Policy on the Sharing of Clinical Information and how to request access to related clinical study documents, see: Change history 13 August 2025 A Correction to this paper has been published: References Schenk, D
Regular follow-up appointments help monitor your progress, adjust dosages if necessary, and ensure that you achieve the best possible results
One datapoint in vehicle group was excluded due to the running wheel got stuck between day -1 to day 0
Christoffersen B, Sanchez-Delgado G, John LM, Ryan DH, Raun K, Ravussin E (2022) Beyond appetite regulation: targeting energy expenditure, fat oxidation, and lean mass preservation for sustainable weight loss