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Physiol Behav 1988

This includes making dietary modifications, increasing physical activity, doing resistance training, and making sure you get enough sleep, says Simonetti

Secondary hypertension is usually associated with an earlier age of onset, no family history, and a clear cause, such as renal or endocrine disorders, or iatrogenic triggers, such as the use of oral contraceptives (131)

A notable new side effect was dysesthesia (skin tingling or sensitivity), reported in about 21% of patients on the highest dose, though generally mild