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Thus, Absolute quantification of Gpx4 isoforms in WT animals, revealed that Low-DHA diets leads to the stimulation of gene expression of all isoforms (between 1.43 and 1.99 times), being the largest stimulation observed for the cytosolic isoform, which, in turn is the most abundant Gpx4 isoform under any circumstance (Figure 3)

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The diminished accumulation of GSAAT attributable to TRX-f1 and NTRC deficiency results in a decrease in the flow of metabolites through the TBS pathway, and a correspondingly lower Chl content ( Figures 4A, B, E, F ), but does not alter the Chl a/b ratio ( Figure 4C )

SC ( n = 36) (Table 4)