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Para embarazo planificado, algunos agentes como semaglutida deben suspenderse al menos 2 meses antes de la concepcin planificada [15] [17] Diagnstico de carcinoma medular de tiroides o MEN-2: Contraindicacin para agonistas GLP-1 con advertencia en caja (semaglutida, liraglutida, dulaglutida) [18] [19] Situaciones que justifican cambio de agente: La intolerancia gastrointestinal persistente tras 12 semanas de tratamiento puede justificar cambio a un agonista GLP-1 alternativo con diferente perfil farmacocintico

Semaglutide is a long-acting GLP-1 receptor agonist

Glutathione acts as a shield, neutralizing free radicals (unstable molecules) before they can cause damage

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