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A Phase 2b, Double-blind, Randomized, Placebo-controlled, Dose-finding, Multi-center, 36-week Safety and Efficacy Study With Open-label Extension (OLE) Period of Tesomet in Subjects With Hypothalamic Obesity

Pruritus was reported in 4%, 2%, and 2% of patients (including adolescents) receiving topiramate 50 mg/day, 100 mg/day, and 200 mg/day, respectively, for migraines in placebo-controlled (2%) clinical trials

Pregnancy and Breastfeeding: Pregnant and breastfeeding women have increased vitamin B12 requirements to support the growth and development of the fetus or infant

Potential Cartilage Assistance: Some research on growth hormone fragments suggests they may support joint health