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In the current review, five eligible studies were excluded from quantitative synthesis due to incomplete/non-extractable data
Extracted nuclei were resuspending in 0.4N H2SO4 and rotated for 4 hours or overnight at 4C to extract histone proteins
For more severe cases, a dermatologist can prescribe a vitamin A derivative in the form of topical retinoids (these could be retinol, tretinoin, or tazarotene) which can help address the bumps, but they can also dry the skin, while steroid creams can help with underlying inflammation and redness but are for short-term use only
