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When varying the grace period between 60 days and 365 days, treatment discontinuation rates at 3 years ranged from 23.3% to 43.6% among GLP-1 receptor agonist users and from 28.8% to 50.6% among SGLT2 inhibitor users

To this regard, it has been reported that the time to conceive is longer in women with body mass index (BMI) superior to 25 kg/m 2 or inferior to 19 kg/m 2 , and that both overweight and obesity are significantly related with reduced pregnancy rate, increased supplies of gonadotrophins and higher miscarriage rate

This dual mechanism distinguishes Mounjaro from exendin-4-based therapies, offering enhanced glycaemic control and weight reduction in type 2 diabetes