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Is anyone aware whether or not diabetes folks will be eligible

The "timing hypothesis" or "critical window" hypothesis, now supported by substantial mechanistic and clinical data, proposes that estrogen's cardiovascular protective effects are contingent on initiating therapy while vascular endothelium remains estrogen-responsive, generally within ten years of menopause onset or before age 60 [8]

Manufacturers and distributors of supplements are responsible for evaluating the safety and labeling of their products before marketing to ensure that they meet all regulatory requirements

Both types can interact with receptors and influence cellular activity