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Talbot K, Wang HY, Kazi H, Han LY, Bakshi KP, Stucky A, Fuino RL, Kawaguchi KR et al (2012) Demonstrated brain insulin resistance in Alzheimers disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline

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Upregulated expression of both eNOS and iNOS (Fig

Effectiveness of saxagliptin tablets was not demonstrated in a 26-week, placebo-controlled, double-blind randomized clinical trial with a 26-week safety extension (NCT03199053) in 164 pediatric patients aged 10 to 17 years with inadequately controlled type 2 diabetes mellitus In the seven, double-blind, controlled clinical safety and efficacy trials of saxagliptin, a total of 4751 (42%) of the 11301 patients randomized to saxagliptin were 65 years and over, and 1210 (10.7%) were 75 years and over