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Archives of Internal Medicine, 130(5), 778-780

More recently, urea-based and pyrazolidine CypD inhibitors with nanomolar affinity have shown robust protection of pancreatic mitochondria and tissue architecture in cerulein- and bile acid-induced AP, confirming that mPTP inhibition is a druggable node that functionally stabilizes mitochondrialER Ca 2+ crosstalk, ROS generation, and cell-death patterns

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I saw my percent body fat go down and my lean muscle increase, which are actually way better markers and metrics of well-being and longevity than a BMI, which often kind of gets it wrong, he says