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[13] We posited that we could design a structured linker that aligned the two proteins in an optimal conformation, preserving the functionality of the original sensor while creating a more compact fusion with better expression and targetability
This scheme illustrates potential therapeutic targets in obesity management by modulating receptors of GLP-1, amylin-calcitonin, and ghrelin pathways
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Next, using Significance Analysis of INTeractome (SAINT) analysis, they found that 39 proteins were labeled by HopF2-BirA, and 111 proteins were labeled by BirA
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