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However, the recently concluded SAVOR-TIMI 53 trial conducted on patients with T2DM with either a history of established CVD or multiple CVD risk factors, has failed to demonstrate the superiority of saxagliptin over placebo in reducing a composite end point of cardiovascular death, nonfatal MI or nonfatal ischemic stroke when added to usual care [142, 143]
Topical Cream/Gel: The Least Effective Glutathione available in topical forms (creams or gels) is the least effective preparation This is because the Glutathione molecule is quite large
TP: Conceptualization, Funding acquisition, Resources, Supervision, Writing review & editing
This suggests that while common gastrointestinal side effects may occur, serious safety concerns like fractures and hypoglycemia are not significantly elevated in older adults compared to placebo
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