They are not recommended in those with personal or family history of multiple endocrine neoplasia 2A, multiple endocrine neoplasia 2B, or medullary thyroid cancer due to concern for long-term thyroid effects.3 Side Effects and their Implications in the ED Gastrointestinal Side effects Mild gastrointestinal side effects are most common with patients experiencing nausea (25-40%), vomiting, diarrhoea, or constipation.3,4 Rarer, more serious presentations include pancreatitis, bowel obstruction, gallbladder disease, which should be actively managed in the ED.3,5 Hypersensitivity reaction These reactions are commonly associated with self-limiting or antihistaminic responsive pruritic rash
374 Ferroptosis in Myasthenia gravis MG is a rare, chronic autoimmune disorder characterized by autoantibodies targeting receptors at the postsynaptic membrane of the neuromuscular junction
Initially limited to APOE genotyping, neurogenomic clinical recommendations have evolved toward broader SNP panels, covering several biological pathways relevant to neurodegeneration
Ferroptosis in atherosclerosis Atherosclerosis is a long-term inflammatory condition marked by the development of lipid-rich plaques within large and medium-sized arteries, leading to diminished blood flow to tissues