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The goal is to lose weight mostly from adipose tissue (fat), rather than muscle, which is essential to maintain the body robust and metabolism active

This setback reflects broader challenges associated with therapies targeting the amyloid-beta pathway, which has dominated Alzheimers research for decades

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Key points to consider when interpreting the evidence: Most studies are short-term , typically lasting fewer than 12 weeks, making it difficult to assess long-term efficacy or safety Results appear more pronounced in older adults or individuals with obesity, compared to younger, healthy populations L-carnitine alone, without dietary or lifestyle changes , is unlikely to produce clinically meaningful weight loss Neither NICE nor the NHS recommends L-carnitine supplementation as part of any weight management pathway