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Description

The pathophysiological basis for the occurrence of elevated BP and the onset of arterial hypertension have been widely studied in recent years

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The affinity of melatonin is five-fold greater for MT1 than MT2

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HIF activation reprograms cellular metabolism by upregulating glycolytic gene expression in inhibiting pyruvate entry into the TCA cycle [53], thereby mediating a shift from oxidative phosphorylation to glycolysis

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