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Body weight matters significantly

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But modern science now shows it acts on multiple metabolic pathways, including: Stimulating your bodys own GLP-1 secretion by activating L-cells in the gut 3 Improving insulin sensitivity in muscle and liver cells 4,5 Reducing inflammation and oxidative stress 6 Activating AMPK (adenosine 5-monophosphate-activated protein kinase) which is known as the metabolic master switch 7,8 Modulating the gut microbiome to support growth of beneficial bacteria that are associated with metabolic improvement 9,10 Put simply, berberine supports the body on multiple levels, touching several of the root factors behind metabolic dysfunction