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B 0 is the baseline motor score, E max is the maximum inhibitory effect, Cp is the apomorphine plasma concentration predicted by the PK model, Ce is the drug concentration at the site of action, EC 50 is the drug concentration that causes 50% of the maximum effect, g is the Hills sigmoid coefficient, and k e0 is the first-order plasma-effect-site equilibration rate constant

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Spinach can also increase the levels of nitric oxide which improves lipid homeostasis and increases the function of the endothelium as well as inducing an anti-hyperglycemic effect, by inhibiting the pancreatic enzyme a-amylase, intestinal a-glucosidase, and inhibiting the phosphatase protein tyrosine 1B present in the liver and skeletal muscle

Nrf2/p-glycoprotein axis is associated with clinicopathological characteristics in colorectal cancer