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I suspect the pill will be priced somewhere around about 80 to start with, progressing to 130 [for the intermediate dose], and maybe 160 for the top dose. With other drug companies developing their own weight-loss pills, however, competition could also drive down the costs of treatment, as first-generation drugs, or those that offer slightly poorer top-line results, command lower prices, said The Economist

Some patients may notice subtle shifts first, such as appetite or portion-size changes

Current clinical trials suggest retatrutide produces greater average weight loss than both semaglutide (Ozempic/Wegovy) and Tirzepatide

Diabetic cardiomyopathy is an important cardiac complication which is accompanied by cardiac hypertrophy [78]