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Activation of 7nAChRs has anti-inflammatory, antiapoptotic, and antioxidant properties through different pathways, which is beneficial in combating neuronal abnormalities seen in ASD [72]

Behavioral outcomes were assessed using Gilliam Autism Rating Scale-2, while dietary intake was quantified through a validated food-frequency questionnaire

The expectation of responsible, ethical utilization of this information for legitimate investigative and scholarly objectives is paramount

Pro-inflammatory cytokines reduce the production of BH4, thus potentially reducing dopamine levels in situations of systemic inflammation.[ref] One study explains: Dopaminergic neurotransmission is very sensitive to inflammation