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Funding Statement This work was supported by grants from The Regional Innovation and Development Joint Fund of National Natural Science Foundation of China (U22A20269), the Fundamental Research Funds for the Central Universities (2042023kf0045), the National Natural Science Foundation of China (82170246) and the National Key R&D Program of China (2018YFC1311300)

Both require S-adenosylmethionine (SAMe) and both reactions occur in mitochondria (Malecki et al., 2022)