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J Cell Biol 170:11011111 Sarkar S, Davies JE, Huang Z, Tunnacliffe A, Rubinsztein DC (2007) Trehalose, a Novel mTOR-Independent Autophagy Enhancer, Accelerates the Clearance of Mutant Huntingtin and -Synuclein

And, the more serious side effects, such as blood clots or congestive heart failure, are likely to occur in individuals who are already treating a preexisting condition, have heart conditions, or in those who are genetically predisposed to these conditions

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