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In chronic pain management, these medications are often used repeatedlysometimes for months or yearswithout fully addressing the underlying cause of inflammation or tissue injury

In this regard, several incretin-based peptide therapies have emerged: once-weekly subcutaneous injections of glucagon-like peptide-1 (GLP-1) receptor agonist semaglutide, available also as a once-daily tablet, and the dual agonist tirzepatide, which interacts with both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors, also administered as a once-weekly subcutaneous injection

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Evidence for a Beneficial Effect of Oral N-Acetylcysteine on Functional Outcomes and Inflammatory Biomarkers in Patients with Acute Ischemic Stroke