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Funding The works of JM and AM, cited in this review, have been supported by grants from the Ferdowsi University of Mashhad, the University of Tehran, and the Iranian National Elite Foundation

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The comparison between phentermine and GLP-1 medications and the phentermine versus semaglutide comparison may also be relevant for patients exploring lower-cost pharmaceutical alternatives when GLP-1 access becomes restricted

A 2015 review of melanotan use and associated clinical outcomes identified eighteen clinical trials and twenty-one clinical case presentations demonstrating melanotan IIs action as a synthetic tanning agent [4]