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This combined approach addresses both the acute oxidative insult and the underlying metabolic capacity and resilience of auditory cells, offering a promising, multi-faceted therapeutic avenue for preventing noise-induced hearing loss and its frequent sequela, tinnitus, by safeguarding the energetic and redox homeostasis of the auditory system see in Figure 2 -

The ox-LDL particle can damage the delicate endothelial lining of the inside of blood vessels

40 Glutathione is quite nontoxic, its lethal dose being quite high, and it is generally well tolerated

Distinct roles of the receptor tyrosine kinases tie-1 and tie-2 in blood vessel formation