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Gene expression profiling studies have reported that GHK-Cu exposure modulates several genes in human cell preparations, with published analysis of the Broad Institute Connectivity Map gene-expression datasets characterising GHK as modulating the expression of many genes and presenting these transcriptome-wide changes as a basis for the compounds range of documented cellular activities [3], making Copper Tripeptide-1 a compound of interest beyond conventional wound biology research

It should not replace diagnosis, imaging, physical therapy, or medical treatment for injuries

10.1111/j.1538-7836.2004.01085.x J Thromb Haemost

Two separate human clinical trials have investigated this compound: Ulcerative Colitis Trial Clinical investigation of this compound in patients with ulcerative colitis examined the compounds GI-protective properties properties that are consistent with its gastric origin and documented activity on intestinal permeability barriers in animal models