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Table 1 A comprehensive overview of various uremic toxins implicated in macrophage activation and the resulting vascular inflammation, particularly in the context of chronic kidney disease

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Monitoring for side effects: Patients starting semaglutide should be closely monitored for serious side effects, like: Pain in the upper part or middle of the stomach that spreads to the back Allergic reaction Decreased urination and swelling of the feet, legs, or ankles Changes in vision Fainting or dizziness Yellow eyes (jaundice), dark urine, or clay-colored stools Rapid heartbeat Sweating, confusion, drowsiness, headache, or blurred vision Customizing a treatment plan: Semaglutide should be tailored to each patients unique health profile, including their cardiovascular risk and comorbidities