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It reacts with hemoproteins and Fe 2+ producing peroxyl and alcoxyl free radicals, which enter to the propagation phase of the lipid peroxidation radical chain reaction

Nonetheless, the pharmacological activation of the GLP-1R is clinically beneficial (179), offering an improved glycaemic control with lower cardiovascular morbidity and without the risk of hypoglycaemia associated with some current anti diabetic drugs (173)