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222 As a Lewy body constituent and a partner of alpha-synuclein, synphilin-1 interacts with -synuclein to diminish the degeneration of neurons in the brain and motor abnormalities in mice with the A53T mutation

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The right dosing schedule can only be determined through medical supervision and ongoing monitoring

In prostate cancer cells androgens have been shown to upregulate the expression of IGF-1R and as a consequence results in increased proliferation and invasion when stimulated with IGF-1 (Pandini et al., 2005)