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To view or add a comment, sign in A positive allosteric modulator acts on the alpha 7 nAChR and causes a conformational change in the receptor which makes it more sensitized to Acetylcholine and therefore Pyridostigmine works more efficiently in Long Covid

Vegans, vegetarians, people over the age 50, anyone with stomach/bowel issues like chronic gastritis, leaky gut, IBS or celiac, and anyone who regularly takes medications such as Metformin, PPIs (used for GERD), H2 Receptor Antagonists (used for peptic ulcers), or anything that interferes with stomach acid production are actually at risk for vitamin B12 deficiency, and should supplement B12 regularly

Brain Res Bull 162:132140

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