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Common side effects include swelling, itching and mild redness in the treated area

21 Neuropsychological scores with the GSH and metal ion correlation analysis are included in this study

The lower molecular weight ( 28 kDa) subunit regulates the activity of the enzyme by reducing the inhibition by GSH (Huang et al., 1993

To our knowledge, this is the first study to perform transcriptomic profiling on metformin treated SW837 rectal cancer cells, and supports a previous study in colon cancer cells, demonstrating metformin-induced alteration of genes involved in reactive oxygen species production, cell cycle, programmed cell death and energy metabolism pathways (68)