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This occurrence is known as cortisol steal, and it usually causes a decrease in progesterone relative to estrogen to occur because cortisol is made from progesterone

doi: 10.1038/nrd.2017.162 33 KhomichO

Intra-articular corticosteroid injections provide a clinically relevant benefit compared to placebo only at short-term follow-up in patients with knee osteoarthritis: a systematic review and meta-analysis

David: It just tickles us because we love things that just seem so unlikely