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Free Radiacal and Oxidative Stress Glutathione is the front-line defense against free radicals and oxidative stress

GHK-Cu's copper coordination complex can undergo structural rearrangement during freezing as ice crystal formation concentrates solutes and shifts local pH, potentially causing copper dissociation from the peptide and subsequent loss of biological activity upon thawing

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Hematoxylin and eosin (H&E) staining of major organs revealed no morphological changes, and the blood sample analysis of liver aminotransferase levels was lower in the Jug-PLGA-NP group than in the other groups [199]