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The bottom-line is CoA is behind the production of hemoglobin, bile, sex and adrenal hormones (steroids), cholesterol and the neurotransmitters acetylcholine and serotonin in your brain

Combining four compounds compounds the uncertainty: potential interactions, cumulative immunogenicity, and effects of long-term exposure are all unstudied

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A smaller placebo-controlled trial showed that oral administration of 300 mg/day of coenzyme Q 10 for 48 to 96 months moderately improved motor symptoms in treated patients (with Levodopa) with re-emerging symptoms but not in patients at an early stage of the disease (67)