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Oral post-treatment with silymarin (50 mg/kg for 30 days) in rats extensively inverted the liver tissue changes induced by diethylnitrosamine and presented a relatively full protection (23)

We evaluated the antioxidant action after administering melatonin in different experimental animal models and tissues: (a) hepatoprotection (decrease in tissue damage)

Methylenetetrahydrofolate reductase (MTHFR) is an FAD-dependent enzyme that plays a key role in one-carbon metabolism by catalyzing the reduction of 5,10 methyleneTHF to 5 methylTHF