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The latest research shows that berberine significantly decreases the expression of GFAP in the Alzheimers disease mice hippocampus, indicating berberine inhibits the overexpression of astrocytes in Alzheimers disease mice

[24] Gfeller D, Grosdidier A, Wirth M, Daina A, Michielin O, Zoete V

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Like other soluble fibers, its believed to promote weight loss in several ways (1): It also feeds the friendly bacteria in your intestine, which turn it into short-chain fatty acids like butyrate, shown to protect against fat gain in some animal studies ( Feeding your gut bacteria may also have other benefits