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Then we had Herman Pontzer on and we talked about metabolic adaptation from the burn side, right the reason you can't marathon your way to weight loss because your body's just going to adjust

Common side effects include gastrointestinal symptoms like nausea , vomiting , and diarrhea , especially during the initial treatment phase

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These include: Nausea and vomiting (very common, affecting more than 1 in 10 patients) Diarrhoea or constipation Abdominal discomfort or bloating Reduced appetite These symptoms often diminish over several weeks as the body adjusts to the medication